Comparative studies of the immunomodulatory activity of tinospora cordifolia and tinospora sinensis. Antioxidant, antihypertensive, antihyperglycemic, and antimicrobial. Tinospora cordifolia herb uses, benefits, cures, side effects. Pdf anti bacterial activity of tinospora cordifolia extracts on. Therefore, in view of this importance many traditionally known medicinal plants have been documented in recent years which possesses various medicinal properties viz, anticancer activity, antidiabetic activity, hepatoprotective activity, antioxidant activity, antimicrobial activity, larvicidal activity, antiinflammatory activity and haemolytic. Anitbacterial activity of tinospora cordifolia willd hook. Hence, the present in vitro study was undertaken to assess the antimicrobial properties of tinospora cordifolia against streptococcus mutans, the most common. Most research has been done in test tubes or in animals.
All these active compounds have immunomodulatory and physiological roles of different types. Antibacterial activity of tinospora cordifolia request pdf. Tinospora is one of the important genera of the family, consisting of about 15 species. Tinospora cordifolia menispermaceae is an herbaceous. Tinospora cordifolia supplement health benefits, dosage. The antibacterial activity of tinospora cordifolia extracts has been assayed against various gram positive and gram negative organisms. In vitro antihiv activity of crude extracts from tinospora. Tinospora cordifolia, antioxidant activity, medicinal plant, antihyperglycemic activity. Tinospora cordifolia commonly named as guduchi in sanskrit belonging to family menispermaceae is a genetically diverse, large, deciduous climbing shrub with greenish yellow typical flowers, found at higher altitude. Conclusion phyto chemical investigation of cow urine sample and medicinal plant extracts will definitely prove the. The antimicrobial activity of azadirachta indica, mimusops. Review of biological activities of tinospora cordifolia. Doubleedged sword against salmonellosis sultan alsuhaibani1 and masood a. Tinospora cordifolia contains many different chemicals that might affect the body.
The present study was aimed at determining the activity of aqueous and methanolic extracts of tinospora cordifolia aetc and metc against salmonella typhimurium. In this paper, we describe a novel polysaccharide rr1, an aglucan, exhibiting unique immune boosting properties. Plants have been one of the important sources of medicines since the beginning of human civilization. The turbidity corresponding to the bacterial growth in different dilutions.
Introduction i t is the need of hour to show the effectiveness of the drug in a disease by laboratory findings. A plant with as diverse a role as tinospora cordifolia is a versatile resource for all forms of life. Free radical scavenging activity of tinospora cordifolia neha upadhyay, showkat a. Tinospora cordifolia is a popular medicinal plant which is used in several. Secondary metabolites including anthraquinones, terpenoids, and saponins were present in many extracts in addition to phenolics. Research article immunestimulatory and therapeutic activity of tinospora cordifolia. One ayurvedic polyherbal formulation ilogenexcel, which contains t.
In vitro antimicrobial activity of tinospora cordifolia. Tinospora cordifolia is a medicinal plant whose status in the field of natural medicine and ayurveda is of the highest. Pdf the present study was carried out to evaluate the in vitro antibacterial activity of aqueous leaf and stem extracts of tinospora cordifolia on. In indian medicinal system, tinospora cordifolia plant is widely used due to its antioxidant, antidiabetic, antiinflammatory, hepatoprotective, immunomodulatory, antineoplastic, and antimicrobial effects 1416. Antimicrobial activity of plant extracts was determined using kirbybauer. Pdf antibacterial activity of stem extracts of tinospora cordifolia. Nelson 1department of biology, college of science, eritrea institute of technology, mai nefhi, eritrea, north east africa 2department of botany, government arts college, ariyalur, tamilnadu, india.
The antimicrobial activity of azadirachta indica, mimusops elengi, tinospora cardifolia, ocimum sanctum and 2% chlorhexidine gluconate on common endodontic pathogens. Lysozymes act as a potent antimicrobial compound against grampositive species shimada et al. The active components of stem bark of tinospora cordifolia were extracted using cold water and organic solvents methanol, diethyl ether and acetone and were tested against staphylococcus aureus using the agar disc diffusion method. Results of antimicrobial activity revealed that these. Tinospora cordifolia guduchi, a reservoir plant for. Methanolic extract was found to be more potent against both the group of bacteria. In present times, this drug has been subjected for. Immune stimulating properties of a novel polysaccharide from the medicinal plant tinospora cordifolia. Comparative analysis of hptlc, secondary metabolites and antioxidant activities of tinospora cordifolia stem powders html full text. Antimicrobial efficiency of tinospora cordifolia and hymenocallis littoralis, medicinal plants were examined using ethanol, methanol, chloroform, dichloromethane, ethyl acetate as solvents a nd found that all the plants parts showed significant activity against all pathogens. Pdf antimicrobial activity of tinospora crispa root extracts.
Antibacterial activity of aqueous, ethanol and chloroform extracts of leaves and stem of tinospora cordifolia hook. Effect of feeding giloy tinospora cordifolia and fenugreek trigonella foenumgraecum on lipid profile in jersey crossbred cows. Tinospora cordifolia, also known as giloy, guduchi or amrita, is used in the treatment of various diseases in the traditional medicinal system in india and is also an immune system modulator. The antibacterial activity of these fractioned extracts from tinosporacordifolia callus and leaf were seen against multi drug resistance bacteria. Antimicrobial activity of tinospora cordifolia extracts. Present communication reports the scientific evaluation of tinospora cordifolia for its medicinal efficacy which includes phytochemical screening, antimicrobial, antioxidant, and anticancer activities of the plant. Khan2 1department of medical laboratory, college of applied medical sciences, qassim university, buraydah, saudi arabia 2department of optometry, college of applied medical sciences, qassim university, buraydah, saudi arabia. Plant samples of tinospora crispa was collected from tangail in march, 2010. Separation and identification of bioactive peptides from.
Rr1 is isolated from a medicinal herb, tinospora cordifolia family minispermaceae, well known in the indian ayurvedic system of medicine for antiinflammatory, antiallergic, antiarthritic, antioxidant. The stem is bitter, stomachic, diuretic, stimulates bile secretion, causes constipation, allays thirst, burning sensation. Yavatikta and ghritakumari all are having antimicrobial activity against common bacteria clinically signs of inflammation are pacified by the drugs. Gv manjusha, k rajathi, jkm alphonse, ks meeraantioxidant potential and antimicrobial activity of andrographis paniculata and tinospora. Antioxidant and antimicrobial properties of tinospora crispa putarwali stems methanolic extract apart from being the primary source of food to other living things, plants also have medicinal value to treat various kinds of diseases. Antimicrobial study is an easy tool for assessing the potential of ayurvedic drugs on various pathological. Pdf the antibacterial activity of the aqueous, ethanol and chloroform extracts from the stems of tinospora cordifolia was studied using disc. The frequent, increasing drug resistance among urinary tract infections utis causing bacteria has made therapy difficult and also lead to greater use of expensive broadspectrum drugs. The aim of this study was to determine the in vitro antimicrobial activity of ethanol, distilled water, methanol and chloroform crude extracts of the roots of tinospora crispa. Dec 23, 20 present communication reports the scientific evaluation of tinospora cordifolia for its medicinal efficacy which includes phytochemical screening, antimicrobial, antioxidant, and anticancer activities of the plant.
Tinospora cordifolia an overview sciencedirect topics. Phytochemical and biological analysis of tinospora cordifolia. It is a promising anticancer herb and may provide benefits for people with diabetes. Evaluation of antimicrobial activity and phytochemical screening of extracts oftinospora cordifolia against some pathogenic microbes dinesh bansal 1, pragya bhasin, anita punia1, and anita r. The aim of the present study was to evaluate the antimicrobial activity of tinospora cordifolia extracts against three standard atcc strains of escherichia coli, staphylococcus aureus and. Antidiabetic activity of tinospora cordifolia willd. Despite centuries of use in traditional medicine to treat various disorders, there is no highquality clinical evidence that it has any effect on diseases.
Evaluation of antimicrobial activity of tinospora cordifolia and. Biological activity in human being references alkaloids berberine, choline, tembetarine. Among the tested extracts, the nhexane and nbutanol crude extracts of t. Clinical evaluation of analgesic activity of guduchi, tinospora cordifolia using animal model. In the current study, in vitro cytotoxic activity of 50% methanolic extract of stem of tinospora cordifolia was. It thrives easily in tropical regions, often growing to great heights, and climbing the trunks of large neem trees. There are reports as already discussed that the plant extracts have active compounds in the form of alkaloids, glycosides, lactones and steroids. Studies on in vitro antibacterial activity of tinospora. Phytochemical screening, antibacterial and antioxidant activity of leaves extract of tinospora cordifolia. Scientific validation of the medicinal efficacy of. Studies on antibacterial activity of extracts from.
Bioactive aqueous extracts of twelve yucatecan plants. Scientific validation of the medicinal efficacy of tinospora. Evaluation of antimicrobial activity and phytochemical. It is an obvious indication that the resulting activity of th e cuonps is not due to any capping agents. Issn 23203862 evaluation of anticancer activity of stem. The present study deals with the antimicrobial activity and phytochemical screening of the two medicinal plants, tinospora cordifolia and euphorbia hirta those are commonly available in india. So far, these properties are identified from the secondary metabolites or aqueous extracts of t. Tinospora cordifolia herb uses, benefits, cures, side. It has been traditionally used for treatment of diabetes, jaundice, chronic diarrhoea, cancer, dermatological diseases, general debility, and asthma. Research article scientific validation of the medicinal efficacy of tinospora cordifolia. Although many researchers have studied the antidiabetic activity of tinospora cordifolia, no satisfactory study was conducted to investigate its efficacy in streptozotocin induced diabetic rats or to explore how this drug acts as an antidiabetic agent. Immunestimulatory and therapeutic activity of tinospora. Thoms were tested on clinical isolates of urinary pathogens viz. The antimicrobial activity was determined by measuring the diameter of zone of inhibition.
Clinical evaluation of tinospora cordifolia wild miers guduci in the management of diabetic foot ulcer abstract. Names of tinospora cordifolia in various languages of the world are also given. Plants are utilized as therapeutic agents since time. Antimicrobial activity of tinospora crispa root extracts article pdf available in international journal of research in ayurveda and pharmacy 33. A study on antihelminthic activity of tinospora cordifolia. Viola species and tinospora cordifolia as herbal antibiotics. Nelson 1department of biology, college of science, eritrea institute of technology. In vitro antibacterial effect of tinospora cordifolia.
Journal of medicinal plants studies tinospora cordifolia. List of various diseases cured by tinospora cordifolia. Evaluation of antinociceptive and antioxidant properties. Assessment of antimicrobial activity of different concentrations of. Tinospora cordifolia guduchi or amrita is an important drug of ayurvedic system of medicine and found mention in various classical texts for the treatment of diseases such as jaundice, fever, diabetes and skin disease etc. Oct 09, 2018 tinospora cordifolia, also known as guduchi or amrita, is an immune system boosting herb that can potently reduce the symptoms of allergic rhinitis. Materials and methods the explants of stem and leaf of tinospora cordifolia were collected in medavakkam, chennai for callus induction.
Antimicrobial activity plant extracts of tinospora cordifolia tc have been reported to have potential against microbial infections. Antioxidant and antimicrobial properties of tinospora. Tinospora cordifolia, which is known by the common names heartleaved moonseed, gaduchi, and giloya, is an herbaceous vine of the family menispermaceae indigenous to the tropical areas of bangladesh,india, myanmar, and sri lanka. The amount of lysozymes that leads to microbial activation of macrophages was found to be higher on treatment with t. The chemical constituents and diverse pharmacological importance. View tinospora cordifolia research papers on academia. Research article scientific validation of the medicinal.
N puranik, kf kammar, s deviantidiabetic activity of tinospora cordifolia willd. Comparative microbicidal efficacy of fractionated extracts from in. The anthelmintic activity of ethanol and aqueous extracts of. How tinospora cordifolia is effective for various diseases is listed in repertory format. Study of the antimicrobial activity of cow urine and. Research article screening of antimicrobial activity of. Antimicrobial activity of tinospora cordifolia extracts against urinary tract infections causing bacteria. Studies on in vitro antibacterial activity of tinospora cordifolia stem. Phytochemical screening, antibacterial and antioxidant activity of.
Antimicrobial activity of crude aqueous extracts of moringa oleifera, azadirachta indica, carica papaya, tinospora cordifolia and curcuma longa against certain bacterial pathogens article pdf. Tinospora cordifolia is one of the constituents of several ayurvedic preparations used in general debility, dyspepsia, fever and urinary diseases. Introduction among plants of economic importance, medicinal and aromatic plants have played a vital role in alleviating human sufferings. Tinospora cordifolia is an important herb of tropical india in ayurvedic system of medicines. Pdf antimicrobial activity of crude aqueous extracts of. There is a growing demand for plant based medicines, health products, pharmaceuticals, food supplements, cosmetics etc. In vitro antimicrobial activity of tinospora cordifolia and. The immunestimulating potential of aetc or metc was determined by measuring the cytokine levels in the. Immune stimulating properties of a novel polysaccharide. Ethyl acetate extract shows 85 percentage of hiv1 rt inhibition. To explore the free radical scavenging activity and total phenolic content of tinospora cordifolia bark extracts and their relation. Evaluation of antinociceptive and antioxidant properties of.
Others might increase the activity of the bodys immune system. Tinospora cordifolia belonging to the family menispermaceae. Issn free radical scavenging activity of tinospora cordifolia. Joy hoskeri depertment of biotechnology, the oxford college of science, bangalore 560 102, department of p. Some chemicals might have activity against cancer cells in test animals. There isnt enough information to know the effects of tinospora. Tinospora cordifolia, also known as guduchi or amrita, is an immune system boosting herb that can potently reduce the symptoms of allergic rhinitis. Evaluation of antimicrobial activity and phytochemical screening of extracts of t. Results of the antimicrobial activity obtained using the disc diffusion assay is summarized in table 1and figure 1. Antimicrobial activity, guduchi, guduchi ghana, physicochemical, tinospora cordifolia. Review of biological activities of tinospora cordifolia abstract. In vitro antiinflammatory activity and tissue culture.
565 28 310 1434 999 1321 1036 522 950 1515 1243 1275 443 598 1113 831 1157 1440 916 736 412 188 623 583 315 357 588 712 443 1242 207 1012 1199 545 266 430 450 104 1190 505 855 650 845 1339